Pizza Roll Stuffed Garlic Knots

Featured in: Everyday Family Favorites

These golden garlic knots start with a unique high-protein dough made from Greek yogurt and self-rising flour. Each knot is hand-rolled, filled with savory pepperoni and a blend of mozzarella and parmesan cheeses, then tied into classic knot shapes. After baking until perfectly golden, they're brushed generously with garlic butter and fresh parsley for maximum flavor. The protein-boosted dough creates an irresistibly chewy texture while keeping carbs in check. These stuffed knots make an ideal party appetizer, game-day snack, or fun dinner addition that both kids and adults will love reaching for.

Updated on Mon, 09 Feb 2026 11:40:00 GMT
Golden-brown Pizza Roll Stuffed Garlic Knots fresh from the oven, brushed with garlic butter and parsley. Save
Golden-brown Pizza Roll Stuffed Garlic Knots fresh from the oven, brushed with garlic butter and parsley. | honeymarble.com

My roommate showed up with a bag of those frozen pizza rolls one Tuesday night, and I watched him microwave them like it was the most normal thing in the world. That's when it hit me—what if we made them from scratch, but better, using actual dough and real cheese? A few kitchen experiments later, these garlic knots became the thing I'd make whenever people came over, because they're foolproof, ridiculously delicious, and somehow feel fancy without the fuss.

I made these for my sister's book club, and honest to god, they disappeared before anyone even sat down. Two people asked for the recipe before they finished their first knot, and one person—who claims to hate cooking—asked if she could watch me make them next time. That's when I knew they'd become a permanent fixture in my rotation.

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Ingredients

  • Greek yogurt: This is your secret weapon—it gives the dough incredible moisture and protein without needing eggs or extra fat, and honestly, you won't taste it at all.
  • Self-rising flour: Saves you the hassle of measuring out baking powder and salt separately, though if you don't have it, the substitution in the notes works perfectly fine.
  • Whey protein powder: Keeps these from feeling like empty carbs, and unflavored or vanilla both work beautifully without changing the savory flavor.
  • Pepperoni: Buy the good stuff if you can, because you're only using 24 slices and quality really shows here.
  • Mozzarella and parmesan blend: The mozzarella gets all melty and gooey while the parmesan adds this sharp, salty finish that makes you reach for another one.
  • Garlic butter: This is brushed on twice—once before baking and once after—so the garlic flavor stays bright and the butter soaks into every crevice.

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Instructions

Set the stage:
Preheat your oven to 400°F and line a baking sheet with parchment paper so cleanup is literally just throwing away the paper.
Build your dough:
Mix the Greek yogurt, self-rising flour, protein powder, garlic powder, and salt in a large bowl until everything comes together into a soft, slightly sticky dough. Knead it for just a minute or two until it feels smooth—you're not making bread, so don't overwork it.
Portion and shape:
Divide the dough into 12 pieces and roll each one into a 6-inch rope on your work surface. The thickness should be consistent so they all bake at the same rate.
Stuff with care:
Flatten each rope slightly, lay 2 slices of pepperoni down the center, and sprinkle a generous pinch of both cheeses on top. The filling should look almost overflowing—that's the goal.
Tie and tuck:
Bring both ends of the dough up and over, pinching to seal, then gently twist into a loose knot shape. Tuck the ends underneath so everything stays together and looks intentional.
First butter brush:
Combine your melted butter with the minced garlic, fresh parsley, and salt in a small bowl. Brush half of this mixture over all the knots before they go into the oven.
Bake to golden:
Bake for 18 to 20 minutes, watching until they're golden brown on top and cooked through. The edges will firm up slightly, but the inside stays soft because of that yogurt in the dough.
Final garlic kiss:
As soon as they come out of the oven, brush with the remaining garlic butter while they're still hot so it soaks in.
Cheesy pepperoni filling oozes from these homemade Pizza Roll Stuffed Garlic Knots, served beside a bowl of warm marinara. Save
Cheesy pepperoni filling oozes from these homemade Pizza Roll Stuffed Garlic Knots, served beside a bowl of warm marinara. | honeymarble.com

My neighbor texted me out of nowhere asking if I'd make these for her dinner party, which felt surreal because it meant they'd somehow become known as my thing. There's something deeply satisfying about a recipe that makes people light up and ask questions, not because it's complicated, but because it tastes like you actually know what you're doing in the kitchen.

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Why This Dough Works So Well

The Greek yogurt base sounds weird until you taste it, and then suddenly everything makes sense. It keeps the knots tender without any heavy fat, the protein powder means they're not just empty calories, and the whole thing comes together faster than you'd expect because you're not waiting for yeast to do its thing. I've made these with different flours and they work fine, but the self-rising version is genuinely foolproof.

Filling Ideas That Actually Work

Pepperoni and cheese is the crowd-pleaser, but I've gotten creative on lazy afternoons and figured out what sticks. Turkey pepperoni works if you want to feel slightly healthier about eating these, and if you're cooking for someone vegetarian, cooked mushrooms with extra parmesan hit surprisingly hard. Whatever you choose, don't skimp on the cheese because that melty interior is honestly the whole point.

Serving and Storing These Right

Fresh and warm is obviously the dream—they're best eaten within an hour of coming out of the oven while the cheese is still stretchy and the outside still has that crisp edge. If you have leftovers, they'll keep in an airtight container for a couple days, and a quick 300-degree oven reheat brings them back to almost-fresh status, though let's be honest, they probably won't last that long.

  • Serve with warm marinara sauce for dipping because the acidity cuts through the richness beautifully.
  • A sprinkle of red pepper flakes or extra parmesan right before serving feels fancy but takes zero extra effort.
  • These are perfect for game day, party prep, or just an afternoon when you want something that tastes indulgent but isn't actually that heavy.
Freshly baked Pizza Roll Stuffed Garlic Knots arranged on a rustic platter, ready for a game-day party spread. Save
Freshly baked Pizza Roll Stuffed Garlic Knots arranged on a rustic platter, ready for a game-day party spread. | honeymarble.com

These knots have become my go-to when I want to impress without stressing, which feels like winning at the cooking game. Once you make them once, you'll understand why they keep asking for the recipe.

Recipe FAQs

Can I make these garlic knots ahead of time?

Yes, you can assemble the knots up to a day in advance and refrigerate them before baking. Brush with garlic butter just before baking. You can also freeze the assembled, unbaked knots for up to 3 months. Bake from frozen, adding a few extra minutes to the cooking time.

What can I use instead of self-rising flour?

Simply mix 1 cup all-purpose flour with 1 1/2 teaspoons baking powder and 1/4 teaspoon salt. This combination provides the same leavening power as self-rising flour and will yield the same soft, pillowy texture for your knots.

Can I make vegetarian or lighter versions?

Absolutely. Replace pepperoni with turkey pepperoni for a lighter option, or use sautéed mushrooms, bell peppers, or spinach for a completely vegetarian version. The filling possibilities are endless—try cooked Italian sausage, sun-dried tomatoes, or even chopped olives.

Why is Greek yogurt used in the dough?

Greek yogurt creates an incredibly soft, tender dough while adding protein and moisture. The acidity in yogurt also helps develop gluten structure, resulting in knots that are chewy yet pillowy. Plus, it keeps the dough lower in fat than traditional butter-based doughs.

What's the best way to reheat leftover knots?

Reheat in a 350°F oven for 5-8 minutes until warmed through and crispy on the outside. Avoid microwaving, as it makes the dough tough and rubbery. For extra freshness, brush with a little melted garlic butter before reheating.

Can I skip the protein powder?

You can omit the protein powder and increase the self-rising flour by about 3 tablespoons. However, the protein powder helps structure the high-moisture dough and boosts nutritional content. If omitting, you may need to chill the dough slightly for easier handling.

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Pizza Roll Stuffed Garlic Knots

Soft golden knots stuffed with cheese and pepperoni, brushed with garlic butter. Made with high-protein dough for a satisfying appetizer.

Prep Time
20 minutes
Time to Cook
20 minutes
Overall Time
40 minutes
Recipe creator Samuel Price


Skill Level Medium

Cuisine American-Italian

Makes 12 Portions

Diet Details None specified

What You'll Need

Protein Dough

01 1 cup Greek yogurt, plain nonfat or low-fat
02 1 cup self-rising flour
03 1 scoop unflavored whey protein powder
04 1/2 teaspoon garlic powder
05 1/2 teaspoon salt

Filling

01 24 slices pepperoni
02 1 cup shredded mozzarella cheese
03 1/2 cup shredded parmesan cheese

Garlic Butter

01 4 tablespoons unsalted butter, melted
02 2 cloves garlic, minced
03 2 tablespoons fresh parsley, chopped
04 1/4 teaspoon salt

Directions

Step 01

Prepare workspace and oven: Preheat oven to 400°F. Line a baking sheet with parchment paper.

Step 02

Combine dough components: In a large mixing bowl, combine Greek yogurt, self-rising flour, protein powder, garlic powder, and salt. Mix until a soft dough forms, then knead briefly until smooth.

Step 03

Portion and shape dough: Divide dough into 12 equal pieces. Roll each piece into a 6-inch rope.

Step 04

Fill dough portions: Flatten each rope slightly and place 2 slices pepperoni and a generous pinch of mozzarella and parmesan cheese in the center.

Step 05

Seal and knot: Pinch the dough to seal the filling, then gently tie each filled rope into a knot, tucking the ends underneath.

Step 06

Arrange for baking: Place all knots on the prepared baking sheet in a single layer.

Step 07

Prepare garlic butter coating: In a small bowl, whisk together melted butter, minced garlic, parsley, and salt. Brush half of this mixture over the knots.

Step 08

Bake until golden: Bake for 18 to 20 minutes until golden brown and cooked through.

Step 09

Finish and serve: Remove from oven and immediately brush with remaining garlic butter. Serve warm.

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Equipment Needed

  • Large mixing bowl
  • Spoon or spatula
  • Measuring cups and spoons
  • Baking sheet
  • Parchment paper
  • Pastry brush

Allergy Info

Review each component for allergen potential and talk to your healthcare provider if unsure.
  • Contains dairy: Greek yogurt, cheese, and butter
  • Contains gluten from flour
  • May contain egg depending on protein powder selection
  • Contains pork from pepperoni

Nutrition per portion

This nutritional breakdown is for informational purposes and shouldn't replace professional dietary advice.
  • Total Calories: 138
  • Fat content: 6 grams
  • Carbohydrates: 12 grams
  • Proteins: 10 grams

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